Practitioner

CHD remains the leading cause of death and disability despite recent improvements in disease management.1,2

Current risk stratification tools that rely on traditional risk factors fail to accurately identify those who are at risk of a Heart Attack. In fact, over 50% of individuals presenting with a severe cardiac event have at most one risk factor or normal cholesterol levels.3

Beyond Cholesterol testing.
Beyond Plaque testing.

Unlike any other test for CHD.

  • Validated in a multi-ethnic population4
  • Outcome data demonstrates clinical utility in identifying at-risk patients5
  • Conforms to current ACC/AHA(ATP IV) guidelines6
  • Motivates patients to adhere to physician recommendations7

 

The Hidden Danger of Unstable Cardiac Lesions

Unstable Cardiac Lesions form over time, often without any signs or symptoms, through a process of continuous arterial injury and repair.

Healthy artery wall VS. Artery wall with Unstable Cardiac Lesion in danger of rupturing


  • Arterial Injury
  • Cell Proliferation
  • Stimulation of new blood Cells
  • Cell Adhesion & Platelet Aggregation
  • Cell Death

An unstable lesion begins to form when oxidised or damaged lipids bind and aggregate on the arterial surface, causing an injury.

The PULS™ Test Clinical Validation In Diagnosing Unstable Cardiac Lesion Rupture

The ability to detect the Unstable Lesions that are likely to rupture prior to the cardiac event is crucial in the area of clinical prevention.
The PULS Test analyses clinically validated, multiplexed serum protein assays to measure proteins related to inflammation, apoptosis, thrombosis, vascular remodelling, and other processes underlying Unstable Cardiac Lesion formation and CHD development.

The Latest AHA Guidelines Recommend Conducting Formal Quantitative CHD Risk Assessments

A patient’s personalised 5-Year diagnosis and prognosis of Unstable Cardiac Lesion Rupture.
A calculated “Heart Age” which shows the patient’s Cardiac Risk Score relative to their Age and Gender group.

PULS Profile

A patient’s personalised 5-Year diagnosis and prognosis of Unstable Cardiac Lesion Rupture.

Heart Age

A calculated “Heart Age” which shows the patient’s Cardiac Risk Score relative to their Age and Gender group.

Lifestyle Changes

Specific recommendations for reducing risk according to clinical guidelines.

Order PULS

PULS is a simple blood test that may be performed for patients 30 years or older as a preventative heart health strategy or for patients with a family history of heart disease.

Register your interest


Protect Your Heart Brochure Quantify Endothelial Damage – Predict ACS Brochure

Predicting Heart Attacks for up to 5 Years with The PULS Test on Home and Lifestyle TV.


Annotated Test Report

References
1.) Murphy, et al. Deaths: Final Data for 2010. National Vital Statistics Reports, 2013; 61; Issue 4
2.) “The Top 10 Causes of Death.” WHO. World Health Organization, 1 May 2014. Web. 10 Mar. 2015.
3.) Sachdeva, et al. Lipid levels in patients hospitalized with coronary artery disease: An analysis of 136,905 hospitalizations in Get With The Guidelines. AHJ. 2009; 157; Issue 1
4.) Cross, et al. Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts. Curr Med Res Opin. 2012 Nov;28; Issue 11:1819-30
5.) Nolan, et al. Analytical performance validation of a coronary heart disease risk assessment multi-analyte proteomic test. Expert Opin Med Diagn. 2013 Mar;7; Issue 2:127-36.
6.) Fleisher, et al. 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery. J Am Coll Cardiol. 2014; 64; Issue 22
7.) *Based on physician and patient testimonials.

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